Flashcards on Macular Diseases: Diagnosis and Treatment
Macular Diseases: Diagnosis and Treatment for Students
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Central serous chorioretinopathy
32 cards
Card 1
Question: What is central serous chorioretinopathy (CSCR)?
Answer: An exudative chorioretinopathy with a neurosensory retinal detachment at the macula (with or without RPE detachment) associated with a thick choroid a
Card 2
Question: Typical patient demographics and age range for CSCR.
Answer: Usually working-age adults, peak age 20–45 (commonly 25–50), and more common in males than females.
Card 3
Question: Describe the typical visual symptoms of CSCR.
Answer: Unilateral painless vision loss (VA 20/20–20/200), central scotoma, metamorphopsia, micropsia, color vision problems, decreased contrast sensitivity,
Card 4
Question: What are common risk factors for developing CSCR?
Answer: Stress, Type A personality, male sex, steroid use (oral, inhaled, injection/IV, topical), elevated cortisol, pregnancy, Helicobacter pylori, ecstasy/E
Card 5
Question: How does steroid use relate to CSCR?
Answer: Exogenous corticosteroids (any route) can precipitate CSCR by activating mineralocorticoid receptors and increasing choroidal hyperpermeability.
Card 6
Question: What is the underlying pathophysiology of CSCR according to the content?
Answer: Leakage from choriocapillaris through focal or diffuse hyperpermeable RPE causes subretinal fluid; RPE dysfunction (loss of active fluid transport and
Card 7
Question: How often is CSCR bilateral?
Answer: Bilateral involvement has been documented in up to 42%, more common in patients over 50.
Card 8
Question: Differentiate acute versus chronic CSCR.
Answer: Acute CSCR often self-resolves within months; if subretinal fluid persists beyond ~3–4 months (or not resolved by 4–6 months) it’s considered chronic
Card 9
Question: What are typical OCT/clinical signs of CSCR?
Answer: Round or oval 'blister-like' neurosensory retinal detachment at the macula with subretinal fluid that can be clear, turbid, or fibrinous; RPE often in
Card 10
Question: Characteristic fluorescein angiography (FA) leakage patterns in CSCR.
Answer: Ink-blot (expanding pinpoint) and smokestack leak patterns; leaks are pinpoint and may spread as FA advances.