Flashcards on Lung Cancer: Overview, Diagnosis, and Treatment

Lung Cancer: Overview, Diagnosis, & Treatment Guide

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What are the two main pathological subtypes of lung carcinoma and their proportion of all cases?

Small Cell Lung Carcinoma (SCLC) – 25%; Non-Small Cell Lung Carcinoma (NSCLC) – 75% (includes squamous cell carcinoma, adenocarcinoma, large cell carc

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Lung cancer

50 cards

Card 1

Question: What are the two main pathological subtypes of lung carcinoma and their proportion of all cases?

Answer: Small Cell Lung Carcinoma (SCLC) – 25%; Non-Small Cell Lung Carcinoma (NSCLC) – 75% (includes squamous cell carcinoma, adenocarcinoma, large cell carc

Card 2

Question: According to the text, what are the main risk factors that increase the risk of developing lung cancer?

Answer: Smoking (over 85% of cases, related to pack-years), asbestos exposure (synergistic effect with smoking), radon, and chronic obstructive pulmonary dise

Card 3

Question: What is the relationship between age and the likelihood of a solitary pulmonary nodule being malignant?

Answer: Older age increases the probability of malignancy; in patients over 50 years old, there is more than a 50% chance of the nodule being malignant.

Card 4

Question: Which radiological examination is the test of choice when lung cancer is suspected?

Answer: Chest CT is the first-line examination.

Card 5

Question: What are the characteristics of a solitary pulmonary nodule that are more indicative of a benign nature?

Answer: Small size (<1 cm), smooth, well-defined margins, dense central calcifications, and stability in size (non-progressive).

Card 6

Question: Which features of a solitary pulmonary nodule are more indicative of malignancy?

Answer: Larger size (>2 cm), irregular margins, eccentric/asymmetric calcification, and increasing size over time.

Card 7

Question: How are SCLC stages divided in the text, and what do they mean?

Answer: Limited stage – tumor confined to the chest and supraclavicular lymph nodes (does not include cervical/axillary nodes); Extensive stage – tumor outsid

Card 8

Question: What local symptoms can tumors affecting the airways cause?

Answer: Cough, hemoptysis, airway obstruction, wheezing, and dyspnea; also recurrent (post-obstructive) pneumonia.

Card 9

Question: What symptoms can arise from compression or local invasion of surrounding structures by a lung tumor?

Answer: Cough, hemoptysis, chest pain, dyspnea, post-obstructive pneumonia, dysphagia, superior vena cava (SVC) syndrome, nerve compression leading to hoarsen

Card 10

Question: What is the main clinical question when a solitary pulmonary nodule is found?

Answer: Whether the lesion is malignant and requires biopsy or resection, as early removal of malignancy can lead to a cure.