Test on Fresh and Frozen Embryo Transfer Outcomes

Question 1: In ovulatory women, studies showed that fresh embryo transfer consistently resulted in a higher live birth rate compared to the freeze-all strategy followed by frozen embryo transfer.

A. Ano

B. Ne

Explanation: One study in ovulatory women (N=2,157) showed a fresh live birth rate of 50.2% compared to 48.7% for frozen. Another study (N=782 non-PCOS women) showed a frozen live birth rate of 33.8% compared to 31.5% for fresh. A third outcome set (N=825) showed a frozen live birth rate of 50% compared to 40% for fresh. Therefore, fresh transfer did not consistently result in a higher live birth rate.

Question 2: According to the provided study materials, which of the following are potential risks associated with the transfer of multiple embryos?

A. Increased likelihood of preterm birth

B. Higher incidence of gestational diabetes

C. Reduced risk of miscarriage

D. Increased chance of twins or triplets

Explanation: The study materials explicitly list 'Twins, triplets, etc.', 'Miscarriage', 'Preterm', 'Gestational Diabetes', and 'Pregnancy induced hypertension / Preeclampsia' as risks associated with the transfer of multiple embryos. Therefore, an increased likelihood of preterm birth, a higher incidence of gestational diabetes, and an increased chance of twins or triplets are all listed risks. A reduced risk of miscarriage is incorrect, as miscarriage is listed as a risk.

Question 3: A medicated cycle for frozen embryo transfer offers a more predictable schedule compared to a natural cycle.

A. Ano

B. Ne

Explanation: One of the advantages listed for a medicated cycle is a 'More predictable schedule'.

Question 4: In a medicated cycle, a day 3 embryo transfer occurs after 5 days of progesterone administration.

A. Ano

B. Ne

Explanation: A day 3 embryo is transferred after 3 days of progesterone administration, and a blastocyst is transferred after 5 days of progesterone administration in a medicated cycle.

Question 5: According to the study materials, what is the recommended action if a progesterone level of > 1.5 ng/ml is measured on the trigger day during a fresh embryo transfer cycle?

A. Proceed with the fresh embryo transfer as planned.

B. Freeze all embryos for a subsequent transfer.

C. Increase the dosage of progesterone support.

D. Delay the trigger day by 24 hours.

Explanation: The study materials state that if the progesterone level is high (> 1.5 ng /ml) on the trigger day, the recommendation is to 'freeze all' embryos instead of proceeding with a fresh transfer.