Flashcards on Radiation Effects on Tissues and Organs

Radiation Effects on Tissues and Organs: A Student Guide

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Which organ systems can suffer life-threatening effects from radiation exposure?

Hematopoietic system, gastrointestinal tract, cardiovascular system, and central nervous system.

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Radiation effects

41 cards

Card 1

Question: Which organ systems can suffer life-threatening effects from radiation exposure?

Answer: Hematopoietic system, gastrointestinal tract, cardiovascular system, and central nervous system.

Card 2

Question: Which tissue is noted as having very severe effects from radiation exposure?

Answer: The skin.

Card 3

Question: State the Rule of Bergonié and Tribondeau about radiosensitivity.

Answer: Tissues are more radiosensitive if their cells are less well differentiated and divide more rapidly.

Card 4

Question: Which cell category is most radiosensitive and give examples.

Answer: Vegetative intermitotic cells (high sensitivity); examples: erythroblasts, intestinal crypt cells, germinal cells of epidermis.

Card 5

Question: Which cell category is least radiosensitive and give examples.

Answer: Fixed postmitotic cells (low sensitivity); examples: nerve cells and muscle cells.

Card 6

Question: Between which groups does connective tissue cell sensitivity lie?

Answer: Intermediate in sensitivity between groups II (differentiating intermitotic) and III (reverting postmitotic).

Card 7

Question: List skin structures that are more sensitive to radiation.

Answer: Keratinocytes, hair follicles, and sebaceous glands are more sensitive.

Card 8

Question: List skin structures that are more resistant to radiation.

Answer: Sweat glands and connective tissue are more resistant.

Card 9

Question: What skin effect typically occurs at doses >2 Gy and how does it change at >7 Gy?

Answer: Epilation (hair loss) occurs; it is temporary above 2 Gy and becomes permanent above about 7 Gy.

Card 10

Question: What skin reaction is expected between 2–10 Gy?

Answer: Erythema.