Flashcards on Intracytoplasmic Sperm Injection (ICSI) Overview
ICSI Overview: A Student's Guide to Intracytoplasmic Sperm Injection
Tap to flip · Swipe to navigate
ICSI vs IVF comparisons
24 cards
Card 1
Question: In trials comparing ICSI and conventional IVF, how did livebirth rates generally compare between groups (examples from Dang 2021 and Wang 2024)?
Answer: Dang 2021: ICSI 35% vs IVF 31% livebirths. Wang 2024: ICSI 33.8% vs IVF 36.6% (no statistically significant difference; adjusted RR ~0.92, p=0.16).
Card 2
Question: What was the effect of ICSI versus conventional IVF on fertilisation per oocyte inseminated/injected in Dang et al. (2021)?
Answer: Fertilisation per oocyte inseminated/injected: ICSI 75.0% (56.9–88.9) vs IVF 66.7% (50.0–83.3).
Card 3
Question: How did fertilisation per oocyte retrieved compare between ICSI and IVF in Dang et al. (2021)?
Answer: ICSI 58.3% (40.0–72.7) vs IVF 55.6% (38.8–70.0).
Card 4
Question: What was reported about abnormal fertilisation rates per oocyte inseminated/injected in Dang et al.?
Answer: Abnormal fertilisation per oocyte inseminated/injected: ICSI 1.3% vs IVF 7.4%.
Card 5
Question: How did total fertilisation failure (TFF) rates compare between ICSI and IVF in Dang 2021 and Wang 2024?
Answer: Dang 2021: ICSI 5% vs IVF 6%. Wang 2024: ICSI 3.6% vs IVF 4.8% (RR 0.76, p=0.18; not statistically significant).
Card 6
Question: In Dang 2021, what proportion of couples had no embryo available for transfer in ICSI versus IVF?
Answer: ICSI: 8 couples (2%); IVF: 21 couples (4%).
Card 7
Question: How did the number of day-3 embryos and good day-3 embryos compare between ICSI and IVF in Dang 2021?
Answer: Number of day-3 embryos median: ICSI 5 (3–8) vs IVF 5 (2–8). Number of good day-3 embryos: ICSI 4 (2–7) vs IVF 3 (2–6).
Card 8
Question: What did Wang et al. (2024) report about implantation rates for ICSI vs IVF?
Answer: Implantation rate: ICSI 564/1642 (34.3%) vs IVF 620/1644 (37.7%); unadjusted RR 0.91 (0.83–1.00), p=0.045 (borderline statistical significance favorin
Card 9
Question: Did Wang et al. find a significant difference in ongoing pregnancy or clinical pregnancy between ICSI and IVF?
Answer: No significant difference: clinical pregnancy ICSI 40.1% vs IVF 42.4% (RR 0.95, p=0.27); ongoing pregnancy ICSI 34.8% vs IVF 37.6% (RR 0.93, p=0.16).
Card 10
Question: What embryological outcome differed between groups in Wang et al. (2024) regarding available embryos on day 3?
Answer: Number of available embryos on day 3 was lower in ICSI: median 4 (2–8) vs IVF 5 (2–9); p=0.0054 (unadjusted) and p=0.0009 (adjusted).