Flashcards on Interstitial Lung Diseases: Overview and Management
Interstitial Lung Diseases: Overview and Management
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Interstitial Lung Disease - Interstitial and Alveolar Disorders
18 cards
Card 1
Question: What are the typical symptoms and radiographic findings in the acute form of hypersensitivity pneumonitis (interstitial inflammation)?
Answer: The acute form often presents with flu-like symptoms (fever, chills, cough, dyspnea). Chest X-ray (CXR) shows pulmonary infiltrates in the acute phase
Card 2
Question: Describe the course of chronic hypersensitivity pneumonitis and its diagnostic difficulty.
Answer: The chronic form is more insidious (slowly progressive) and more challenging to diagnose.
Card 3
Question: What is the primary treatment for hypersensitivity pneumonitis caused by exposure?
Answer: Removal of the causative agent and sometimes administration of glucocorticoids.
Card 4
Question: What are the main clinical and laboratory features of eosinophilic pneumonia?
Answer: It presents with fever and peripheral eosinophilia; it can be acute or chronic.
Card 5
Question: What are the radiological findings in eosinophilic pneumonia?
Answer: CXR shows peripheral pulmonary infiltrates.
Card 6
Question: What is the treatment for eosinophilic pneumonia, and what is its typical course?
Answer: Glucocorticoids are usually very effective, but relapses can occur.
Card 7
Question: How do ILDs with granulomas (e.g., EGPA) relate to the category of eosinophilic and hypersensitivity disorders?
Answer: There is significant overlap between this category and ILDs associated with granulomas.
Card 8
Question: What do IgG antibodies cause in anti-GBM disease (Goodpasture's)?
Answer: An autoimmune attack against the glomerular and alveolar basement membranes (Type II hypersensitivity), leading to hemorrhagic pneumonitis and glomeru
Card 9
Question: How does anti-GBM disease typically manifest clinically?
Answer: Usually hemoptysis and dyspnea; renal failure may occur due to proliferative glomerulonephritis.
Card 10
Question: How is anti-GBM (Goodpasture's) disease diagnosed and treated?
Answer: Diagnosis: tissue biopsy and serological testing for anti-GBM antibodies. Treatment: plasmapheresis, cyclophosphamide, and corticosteroids.