Test on Dupuytren's Disease: Pathology and Management

Question 1: A single injury is considered a direct cause of Dupuytren's disease.

A. Ano

B. Ne

Explanation: A single injury can initiate clinically evident Dupuytren's disease in a genetically predisposed patient, but it does not cause the disease. The study materials state that trauma can initiate Dupuytren's disease, but not cause it.

Question 2: According to the provided study materials, which of the following conditions is associated with Dupuytren's disease?

A. Heavy manual labor

B. Diabetes

C. Epilepsy

D. Acquired immunodeficiency syndrome (AIDS)

Explanation: The study materials state that Dupuytren's disease is associated with diabetes, alcoholism, epilepsy, smoking, acquired immunodeficiency syndrome (AIDS), and vascular disorders. It also explicitly mentions that the concept of heavy work causing Dupuytren's disease has not held up to closer scrutiny.

Question 3: The central cord of Dupuytren's disease rarely results in a PIP joint contracture.

A. Ano

B. Ne

Explanation: The study materials state that 'Because of this attachment distal to the PIP joint, the central cord frequently results in a PIP joint contracture.'

Question 4: Which of the following normal fascial structures coalesce, thicken, and contract to form a pathologic spiral cord in Dupuytren's disease?

A. Pretendinous band

B. Spiral band of Gosset

C. Lateral digital sheath

D. Natatory ligament

Explanation: The pathologic spiral cord originates from five separate fascial structures: pretendinous band, spiral band of Gosset, lateral digital sheath, vertical band, and Grayson’s ligament. The natatory ligament is specifically mentioned as the 'only part of the palmar digital junction’s web coalescence not involved with the spiral band'.

Question 5: Closed enzymatic fasciotomy is an investigational procedure for Dupuytren's disease.

A. Ano

B. Ne

Explanation: The study materials state, "It is hoped that in the near future, the investigational procedure closed enzymatic fasciotomy 7 will be an approved therapy..." and also list it as "enzymatic fasciotomy (experimental)".