Flashcards on Chronic Hand and Upper Extremity Infections

Chronic Hand & Upper Extremity Infections: Student Guide

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What CD4+ T-cell count is now considered diagnostic of AIDS regardless of symptoms?

Less than 200 cells/mm3.

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HIV/AIDS

57 cards

Card 1

Question: What CD4+ T-cell count is now considered diagnostic of AIDS regardless of symptoms?

Answer: Less than 200 cells/mm3.

Card 2

Question: At approximately what CD4+ count do most patients with truly opportunistic infections present?

Answer: Less than 100 cells/mm3.

Card 3

Question: Which CD4+ T-cell count range indicates highest risk for death from life‑threatening opportunistic infections?

Answer: Below 50 cells/mm3.

Card 4

Question: What is the hallmark of HIV disease in terms of immune dysfunction?

Answer: Quantitative and qualitative CD4+ T-cell dysfunction.

Card 5

Question: Besides CD4+ T cells, which other immune cells show functional abnormalities in advanced HIV disease?

Answer: B lymphocytes, natural killer cells, and neutrophils.

Card 6

Question: What happens to lymphoid tissue architecture in advanced HIV disease?

Answer: There is almost total dissolution of lymphoid tissue architecture.

Card 7

Question: Which two laboratory measures together provide the best prognostic estimate of HIV clinical course?

Answer: Viral load (plasma HIV RNA) and CD4+ cell count.

Card 8

Question: Name three clinical stages in the spectrum of HIV infection.

Answer: 1) Initial asymptomatic (incubation) stage; 2) Acute retroviral syndrome (primary infection); 3) Chronic persistent lymphadenopathy/clinical latency (

Card 9

Question: How long can the chronic latency (category A) stage last?

Answer: Up to 10 years.

Card 10

Question: What defines AIDS according to the provided content?

Answer: Development of serious opportunistic infections, neoplasms, or other life‑threatening manifestations from progressive HIV‑induced immunosuppression.